JavaScript is off. Please enable to view full site.

GSK halts three trials of respiratory virus vaccine in pregnant women

GSK halts three trials of respiratory virus vaccine in pregnant women

Monday, February 28, 2022, 17:16 GMT+7
GSK halts three trials of respiratory virus vaccine in pregnant women
GSK logo is displayed in this illustration taken January 17, 2022. Photo: Reuters

Britain's GSK said on Monday it had halted enrolment and vaccination in three trials of its experimental vaccine against the respiratory syncytial virus (RSV) in pregnant women, the latest setback in developing a vaccine for the microbe.

GSK said on Feb. 18 that it had paused a late-stage trial, dubbed "GRACE," as well as two other studies, based on safety recommendations from an independent committee but did not give further details on what had prompted the recommendations. 

RSV is a leading cause of pneumonia in toddlers and the elderly, but vaccine development has been plagued by setbacks for decades. However, many drugmakers are now working to bring a candidate to the market over the next few years.

GSK, the world's biggest vaccine maker by sales, reiterated on Monday that the halts did not affect another trial of its RSV vaccine candidate for adults aged 60 and over, adding that analysis of the safety data from the maternal trials is ongoing.

RSV vaccines are seen as an opportunity for GSK to deliver on pledges to boost its drug development success rate, where it has long lagged industry peers. GSK's shot for pregnant women was aimed at conferring immunity to protect unborn children.

Its vaccine for the elderly, another major vulnerable population, has been regarded by analysts as a potential big RSV market, with trial results expected in the first half this year.

Britain's GSK said on Monday it had halted enrolment and vaccination in three trials of its experimental vaccine against the respiratory syncytial virus (RSV) in pregnant women, the latest setback in developing a vaccine for the microbe.

GSK said on Feb. 18 that it had paused a late-stage trial, dubbed "GRACE," as well as two other studies, based on safety recommendations from an independent committee but did not give further details on what had prompted the recommendations. 

RSV is a leading cause of pneumonia in toddlers and the elderly, but vaccine development has been plagued by setbacks for decades. However, many drugmakers are now working to bring a candidate to the market over the next few years.

GSK, the world's biggest vaccine maker by sales, reiterated on Monday that the halts did not affect another trial of its RSV vaccine candidate for adults aged 60 and over, adding that analysis of the safety data from the maternal trials is ongoing.

RSV vaccines are seen as an opportunity for GSK to deliver on pledges to boost its drug development success rate, where it has long lagged industry peers. GSK's shot for pregnant women was aimed at conferring immunity to protect unborn children.

Its vaccine for the elderly, another major vulnerable population, has been regarded by analysts as a potential big RSV market, with trial results expected in the first half this year.

Reuters

More

Read more

Disasters cost $268 billion in 2022: Swiss Re

Natural and man-made catastrophes have caused $268 billion of economic losses so far in 2022, chiefly driven by Hurricane Ian and other extreme weather disasters, reinsurance giant Swiss Re estimated Thursday

1 day ago
;

Photos

VIDEOS

‘Taste of Australia’ gala dinner held in Ho Chi Minh City after 2-year hiatus

Taste of Australia Gala Reception has returned to the Park Hyatt Hotel in Ho Chi Minh City's District 1 after a two-year hiatus due to the COVID-19 pandemic

Vietnamese woman gives unconditional love to hundreds of adopted children

Despite her own immense hardship, she has taken in and cared for hundreds of orphans over the past three decades.

Vietnam’s Mekong Delta celebrates spring with ‘hat boi’ performances

The art form is so popular that it attracts people from all ages in the Mekong Delta

Vietnamese youngster travels back in time with clay miniatures

Each work is a scene caught by Dung and kept in his memories through his journeys across Vietnam

Latest news