Vietnam documented two more COVID-19-related deaths on Tuesday morning, taking the death toll to eight.
The patients had a history of kidney failure, Nguyen Truong Son, Deputy Minister of Health said.
One of the patients was 65 years old and lived in Da Nang, a tourist city on the central coast and an outbreak epicenter at the moment.
He had a history of end-stage renal failure and septicemia, a serious bloodstream infection.
He was treated for kidney disease at Da Nang Hospital for five months before being discharged on July 24.
He tested positive for the novel coronavirus on July 28 and was intubated as well as put on a ventilator at Da Nang Hospital.
His conditions deteriorated from July 29 to August 2.
He went into a coma at 7:45 am and died of end-stage chronic kidney failure, septicemia, acute heart failure, and COVID-19 at 8:30 am, doctors said.
The second patient was 62 years old and had a registered address in Da Nang.
She was admitted to Da Nang Hospital for kidney disease treatment on July 18.
The woman was transferred to Hue Central Hospital, located in Thua Thien-Hue Province about 90km north of Da Nang, on July 30.
She suffered difficulty breathing and was unwilling to eat one day later.
On August 1, she was put on a ventilator at 3:00 am, went into a coma at 7:00 am, and suffered septic shock as well as multiple organ failure at 5:00 pm.
She underwent renal dialysis while still on mechanical ventilation on August 2.
The patient was on the verge of death on Monday before being pronounced dead at 2:30 am on Tuesday.
Doctors said she had died of end-stage renal failure, septic shock, multiple organ failure, and COVID-19.
Some more coronavirus patients are at high risk of death due to their old age and underlying conditions, Deputy Minister Son warned.
Vietnam has logged a total of 652 COVID-19 cases, including 307 imported ones, since January, when the coronavirus outbreak first hit the country, according to the Ministry of Health.
The country has announced 374 recoveries and eight virus-related fatalities who all had serious pre-existing conditions.
Two hundred and five local infections have been linked to Da Nang since July 25, after Vietnam had gone 99 days with no documented community transmission.
The 205 cases consist of 142 in Da Nang, 44 in Quang Nam, three in Quang Ngai Province, three in Dak Lak Province, one in Dong Nai Province, eight in Ho Chi Minh City, two in Hanoi, one in Ha Nam Province, and one in Thai Binh Province.