The Ministry of Health announced 6,580 more COVID-19 cases on Thursday, alongside 1,731 recoveries and 59 fatalities.
The latest cases, including four imported and 6,576 local transmissions, were reported in 49 provinces and cities, the health ministry said, noting that 2,889 patients were detected in the community.
Ho Chi Minh City recorded 981 of the domestically-transmitted infections, Binh Duong Province 948, Dong Nai Province 939, Kien Giang Province 478, An Giang Province 381, Tien Giang Province 263, Tay Ninh Province 240, Dak Lak Province 210, Soc Trang Province 198, Binh Thuan Province 194, Can Tho City 186, Long An Province 178, Tra Vinh Province 123, Ha Giang Province 110, Hanoi 100, Ba Ria-Vung Tau Province 98, Quang Nam Province 42, Khanh Hoa Province 34, and Da Nang 13.
Vietnam had confirmed 7,089 locally-acquired infections on Wednesday.
The country has registered 941,159 community transmissions in 62 out of its 63 provinces and cities since the fourth virus wave emerged on April 27, 832,589 of them having recovered from the respiratory disease.
Ho Chi Minh City has been hit the hardest with 435,717 patients, followed by Binh Duong Province with 236,241, Dong Nai Province with 69,138, Long An Province with 35,287, Tien Giang Province with 17,479, An Giang Province with 12,094, Tay Ninh Province with 11,691, Kien Giang Province with 10,740, Dong Thap Province with 10,135, Khanh Hoa Province with 9,102, Ba Ria-Vung Tau Province with 5,048, Da Nang with 4,995, and Hanoi with 4,924.
Vietnam detected only 1,570 locally-transmitted infections in total in the previous three waves.
The health ministry recorded 1,731 recoveries on Thursday, taking the total to 835,406.
The toll has soared to 22,342 deaths after the ministry registered 59 fatalities on the same day, including 28 in Ho Chi Minh City and 13 in Binh Duong Province.
Vietnam has found 946,043 infections since the COVID-19 pandemic first hit it early last year.
Health workers have administered almost 85 million vaccine doses, including 774,054 shots on Wednesday, since inoculation was rolled out on March 8.
Over 26 million people have been jabbed twice.
Health authorities target to inoculate at least two-thirds of a population of nearly 98 million people against COVID-19 by the first quarter of next year.