The number of people infected by a mystery SARS-like virus that has killed two people in China is likely hundreds more than officially reported, researchers have said.
Chinese authorities have said pneumonia linked to the virus has hit at least 41 people in the country, with the outbreak centered around a seafood market in the central city of Wuhan.
But a paper published Friday by scientists with the MRC Centre for Global Infectious Disease Analysis at Imperial College in London said the number of those affected in the city was likely to be well over a thousand.
The scientists at the Center - which advises bodies including the World Health Organization - said they estimated a "total of 1,723 cases" in Wuhan would have been infected as of January 12.
The researchers took the number of cases reported outside China so far - two in Thailand and one in Japan - to infer how many were likely infected in the city, based on international flight traffic data from Wuhan's airport.
"For Wuhan to have exported three cases to other countries would imply there would have to be many more cases than have been reported," Professor Neil Ferguson, one of the authors of the report, told the BBC.
"I am substantially more concerned than I was a week ago," adding, however, that it was "too early to be alarmist".
"People should be considering the possibility of substantial human-to-human transmission more seriously than they have so far," he added, saying it was "unlikely" that animal exposure was the main source of infection.
Two people are known to have been killed by the virus, a pathogen from the same family as the deadly SARS virus - even as health authorities around the world sought to assure the public that the overall risk of infection remained low.
Authorities in Hong Kong have stepped up detection measures, including rigorous temperature checkpoints for inbound travelers from the Chinese mainland.
The US said from Friday it would begin screening flights arriving from Wuhan at San Francisco airport and New York's JFK - which both receive direct flights - as well as Los Angeles, where many flights connect.